U-GEMMs

Cardio-metabolic Disease

In order to reflect the highly prevalent human situation of cardio-metabolic risk and to elucidate mechanisms, well-characterized mouse models which could develop obesity, insulin resistance or significant atherosclerosis are necessary.

Mice
Strain Name:C57BL/6Smoc-Ins2em3(C96Y)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190096
Disease Connection:diabetes
Mice
Strain Name:C57BL/6Smoc-Irs1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190827
Disease Connection:type 2 diabetes mellitus
Mice
Strain Name:C57BL/6Smoc-Kdm3Aem1Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:obesity
Mice
Strain Name:C57BL/6Smoc-Ldb3em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:dilated cardiomyopathy 1C
Mice
Strain Name:C57BL/6Smoc-Ldlrem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210198
Disease Connection:familial hypercholesterolemia, fatty liver disease
Mice
Strain Name:B6;129S-Leptm1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-00034
Disease Connection:abdominal obesity-metabolic syndrome, abdominal obesity-metabolic syndrome 1, non-alcoholic fatty liver disease, obesity, type 2 diabetes mellitus
Mice
Strain Name:C57BL/6Smoc-Leprem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190663
Disease Connection:type 2 diabetes mellitus, obesity
Mice
Strain Name:C57BL/6Smoc-Lgals3em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190107
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Lrp1em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2101319
Disease Connection:cardiomyopathy, Alzheimer's disease
Mice
Strain Name:C57BL/6Smoc-Lrrc10em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201002
Disease Connection:dilated cardiomyopathy
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