hMASP2
Nomenclature
C57BL/6Smoc-Masp2em1(hMASP2)/Smoc
Cat. NO.
NM-HU-2000076
Strain State
Repository Live
Gene Summary
Gene Symbol
Masp2
Model Description
Validation Data
Fig1. Detection of MASP2 expression in liver by RT-PCR.
Wild type: only one band at 479 bp with primers F1/R1(mMasp2);
Homozygous: only one band at 338 bp with primers F2/R2(hMASP2);
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig2. Detection of hMASP2 expression in liver in HO hMASP2 mice by western blot.
Abbr. HO, homozygous; WT, wild type.
Note: The anti-human MASP2 antibody cross-reacted with mouse MASP2 and humanized MASP2.
Fig3. Detection of hMASP2 expression in liver in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig4. Detection of hMASP2 expression in kidney in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig5. Detection of IgA expression in liver in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig6. Detection of IgA expression in kidney in HO hMASP2 mice by IHC.
Abbr. HO, homozygous; WT, wild type.
Fig7. No obvious pathological features were found in liver in HO hMASP2 mice.
Abbr. HO, homozygous; WT, wild type.
Fig8. No obvious pathological features were found in kidney in HO hMASP2 mice.
Abbr. HO, homozygous; WT, wild type.
Fig9. Detection of mC3 expression in serum by ELISA.
Abbr. HO, homozygous; WT, wild type.
You may also like
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
Learn moreOur vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
Learn more
