U-GEMMs

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:NOD-PrkdcscidIl2rgem1Kitlem1(hKITLG)/Smoc
Strain State:Developing | Cat. NO.:NM-HU-2000039
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Mifem3(hMIF)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000030
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Tgfb1tm1(hTGFB1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200243
Mice
Strain Name:C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000062
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200004
Mice
Strain Name:C57BL/6Smoc-Tnfsf11em3(hTNFSF11)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210366
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfsf13btm1(hTNFSF13B)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200238
Mice
Strain Name:C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225069
Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000064
Research Application:Asthma research;drug screening
Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200269
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