U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-H2-D1em1(hB2M/HLA-A2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210010
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-H2-D1em1(hB2M/HLA-A2.1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234398
Mice
Strain Name:C57BL/6Smoc-B4galnt1tm(hB4GALNT1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220337
Mice
Strain Name:C57BL/6Smoc-B4galt1tm1(hB4GALT1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234378
Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00107
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210353
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210349
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Vtcn1em1(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190004
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190075
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Bace1tm(hBACE1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220263
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