U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210008
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000084
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Nectin2tm1(hNECTIN2)Pvrigem1(hPVRIG)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231148
Mice
Strain Name:C57BL/6Smoc-Ramp2em(hRAMP2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230044
Mice
Strain Name:C57BL/6Smoc-Ramp3tm(hRAMP3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230045
Mice
Strain Name:C57BL/6Smoc-Rbp4em1(hRBP4)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234023
Mice
Strain Name:C57BL/6Smoc-Ren1tm(hREN)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220369
Mice
Strain Name:C57BL/6Smoc-Ren1em(hREN)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220370
Mice
Strain Name:C57BL/6Smoc-Tg(hREN)1Smoc
Strain State:Developing | Cat. NO.:NM-TG-230036
Mice
Strain Name:C57BL/6Smoc-Rhoem1(hRHO)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234891
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