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A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

Model Organisms：Mice Product & Service：Zap70-W163C Research field：Ankylosing Spondylitis

Published date：2023-05-26 | References：Journal of Nanobiotechnology

Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery

Model Organisms：Mice Product & Service：huHSC-(M-NSG) Research field：antitumor immunity

Published date：2023-05-19 | References：ACS Nano

Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy

Model Organisms：Mice Product & Service：Acod1-flox Research field：cancer immunotherapy

Published date：2023-04-28 | References：Science Advances

Ameliorating parkinsonian motor dysfunction by targeting histamine receptors in entopeduncular nucleus–thalamus circuitry

Model Organisms：Mice Product & Service：Slc17a6-IRES-Cre Research field：parkinsonian motor dysfunction

Published date：2023-04-17 | References：PNAS

Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression

Model Organisms：Mice Product & Service：LCP1-KO Research field：osteoarthritis

Published date：2023-04-05 | References：Sciences Advances

Multilineage commitment of Sca-1+ cells in reshaping vein grafts

Model Organisms：Mice Product & Service：Pdgfra-Flox Research field：the reshaping of vein grafts

Published date：2023-04-01 | References：Theranostics

IL-37 Attenuates Platelet Activation and Thrombosis Through IL-1R8 Pathway

Model Organisms：Mice Product & Service：Sigirr-flox Research field：coronary artery disease

Published date：2023-03-31 | References：Circulation Research

DNA repair mechanisms that promote insertion- deletion events during immunoglobulin gene diversification

Model Organisms：Mice Product & Service：Apex2-ko;Polh-ko Research field：immunoglobulin gene diversification

Published date：2023-03-24 | References：SCIENCE IMMUNOLOGY

Exosome-derived circCCAR1 promotes CD8+T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Model Organisms：Mice Product & Service：NMG Research field：hepatocellular carcinoma；exosome

Published date：2023-03-18 | References：Molecular Cancer

Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical Model of Human Non-Small Cell Lung Carcinoma

Model Organisms：Mice Product & Service：M-NSG Research field：Non-Small Cell Lung Carcinoma

Published date：2023-03-12 | References：International Journal of Molecular Sciences

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