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U-GEMMs

About 42,200 results
Mice

hCCR2

Strain Name：C57BL/6Smoc-Ccr2em2(hCCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18026

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

h4-1BB(2)/hCD3E(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

Ccr2-2A-DreERT2

Strain Name：C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200023

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190011

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hCD38(2)

Strain Name：C57BL/6Smoc-Cd38em2(CD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190059

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

Mice

hCD19

Strain Name：C57BL/6Smoc-Cd19em1(hCD19) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00110

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

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