U-GEMMs

Cardio-metabolic Disease

In order to reflect the highly prevalent human situation of cardio-metabolic risk and to elucidate mechanisms, well-characterized mouse models which could develop obesity, insulin resistance or significant atherosclerosis are necessary.

Mice
Strain Name:C57BL/6Smoc-Myocdem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:patent ductus arteriosus, dilated cardiomyopathy
Mice
Strain Name:C57BL/6Smoc-Ncoa6em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:dilated cardiomyopathy
Mice
Strain Name:C57BL/6Smoc-Neil1em1Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:abdominal obesity-metabolic syndrome, obesity
Mice
Strain Name:C57BL/6Smoc-Nexnem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:dilated cardiomyopathy 1CC
Mice
Strain Name:C57BL/6Smoc-Nos1em1Smoc
Strain State:Developing | Cat. NO.:NM-KO-240406
Disease Connection:hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, achalasia, hypertrophic pyloric stenosis
Mice
Strain Name:C57BL/6Smoc-Nos3em1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-18022
Disease Connection:hypertrophic cardiomyopathy, nephrogenic diabetes insipidus, essential hypertension, persistent fetal circulation syndrome
Mice
Strain Name:C57BL/6Smoc-Nppaem1Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:hypertension
Mice
Strain Name:C57BL/6Smoc-Npy1Rem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190999
Disease Connection:obesity
Mice
Strain Name:C57BL/6Smoc-Pdcd1em3Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190423
Disease Connection:cystitis, dilated cardiomyopathy, systemic lupus erythematosus
Mice
Strain Name:C57BL/6Smoc-Pdlim5em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:dilated cardiomyopathy
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