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A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

Model Organisms：Mice Product & Service：Zap70-W163 Research field：Ankylosing Spondylitis

Published date：2023-05-26 | References：Journal of Nanobiotechnology

Exosome-derived circCCAR1 promotes CD8+T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Model Organisms：Mice Product & Service：NMG Research field：hepatocellular carcinoma；exosome

Published date：2023-03-18 | References：Molecular Cancer

TREM2+ macrophages suppress CD8+ T-cell infiltration after transarterial chemoembolisation in hepatocellular carcinoma

Model Organisms：Mice Product & Service：Trem2-KO Research field：hepatocellular carcinoma

Published date：2023-03-06 | References：JOURNAL OF HEPATOLOGY

Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury

Model Organisms：Mice Product & Service：Me1-Flox Research field：Hepatic Ischemia/Reperfusion Injury；ferroptosis

Published date：2023-02-25 | References：ADVANCED SCIENCE

A Cre knockin mouse reveals specifc expression of Agouti gene in mesenchymal lineage cells in multiple organs and provides a unique tool for conditional gene targeting

Model Organisms：Mice Product & Service：a-IRES-Cre Research field：Cre mice

Published date：2023-01-13 | References：SpringerLink

An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ

Model Organisms：Mice Product & Service：Il2rg Research field：immunity

Published date：2022-12-07 | References：Molecular Therapy

Self-assembly of X-shaped antibody to combine the activity of IgG and IgA for enhanced tumor killing

Model Organisms：Mice Product & Service：hCD89&hFCRN Research field：immunity

Published date：2022-11-14 | References：Theranostics

IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation

Model Organisms：Mice Product & Service：DDX5-flox, sIL36R-flox, K14-Cre Research field：atopic dermatitis and psoriasis

Published date：2022-10-21 | References：nature immunology

SEMA7AR148W mutation promotes lipid accumulation and NAFLD progression via increased localization on the hepatocyte surface

Model Organisms：Mice Product & Service：Sema7a -R148W Research field：NAFLD

Published date：2022-08-08 | References：jci insight

T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies

Model Organisms：Mice Product & Service：NMG Research field：immune system,CAR-T

Published date：2022-07-26 | References：nature communications

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