U-GEMMs

Lectures

Lectures

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6JSmoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200002
Research Application:corona virus related research
Mice
Strain Name:C57BL/6JSmoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-220128
Mice
Strain Name:C57BL/6JSmoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190077
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6JSmoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210409
Research Application:药物筛选;免疫治疗
Mice
Strain Name:C57BL/6JSmoc-Tnfrsf9tm2(TNFRSF9)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200272
Mice
Strain Name:C57BL/6JSmoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200279
Mice
Strain Name:C57BL/6JSmoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210357
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6JSmoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00048
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6JSmoc-Abcc2tm1(hABCC2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200254
Mice
Strain Name:C57BL/6JSmoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200218
Research Application:Corona virus related research
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