U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190128
Research Application:Wnt1 signaling pathway, cancer research, etc
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190087
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18053
Research Application:Tumor research; drug screening
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Kozak-hIGF1R-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-231795
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220130
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Kozak-hNTN1-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-233967
Mice
Strain Name:FVB-Gt(ROSA)26Sorem1(pAPOE-CYP3A4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18032
Research Application:metabolism
Mice
Strain Name:FVB-Gt(ROSA)26Sorem1(Gut-CYP3A4-IRES-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-18033
Research Application:metabolism
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225096
Mice
Strain Name:C57BL/6Smoc-Rab31em1(hRAB31*Y76F/Y86F/Y137F)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210419
Email Back to top