U-GEMMs

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

Mice
Strain Name:C57BL/6Smoc-Psen1em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:Alzheimer's disease 3, Alzheimer's disease, Alzheimer's disease 4
Mice
Strain Name:C57BL/6Smoc-Psen2em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD
Disease Connection:Alzheimer's disease, Alzheimer's disease 4
Mice
Strain Name:C57BL/6Smoc-Ptenem1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-18004
Mice
Strain Name:C57BL/6Smoc-Ptenem3Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-18002
Disease Connection:autism spectrum disorder, prostate cancer, Cowden syndrome
Mice
Strain Name:C57BL/6Smoc-Ptger4em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2100609
Disease Connection:dilated cardiomyopathy
Mice
Strain Name:C57BL/6Smoc-Tgtn(pThy1-MAPT-P301L(tauP301L))1Smoc
Strain State:Developing | Cat. NO.:NM-KI-235095
Mice
Strain Name:C57BL/6Smoc-Tgtn(pThy1-MAPT-P301L(tauP301L))2Smoc
Strain State:Developing | Cat. NO.:NM-KI-235096
Mice
Strain Name:C57BL/6Smoc-Ptpn11em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-231881
Disease Connection:juvenile myelomonocytic leukemia, Noonan syndrome 1, disease of metabolism
Mice
Strain Name:C57BL/6Smoc-Ptsem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-200641
Disease Connection:BH4-deficient hyperphenylalaninemia A
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-tdTomato-polyA-loxp2272-polyA-Wpre-Tag-IRES-EGFP-2A-Luciferase-loxp-loxp2272)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200033
Research Application:Spontaneous tumor model
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