U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00102
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Lag3tm1(hLAG3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00137
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00111
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Sema4dem1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190034
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000099
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tmem173tm1(hTMem173)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000105
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18013
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190056
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hCD274)Kdrtm2(hKDR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000102
Research Application:Immunotherapy,cancer research,drug screening
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