U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Trpa1tm1(hTRPA1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234698
Mice
Strain Name:C57BL/6Smoc-Tshrtm1(hTSHR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232156
Mice
Strain Name:C57BL/6Smoc-Tshrtm2(hTSHR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232157
Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000064
Research Application:Asthma research;drug screening
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Tslptm(hTSLP)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220426
Mice
Strain Name:C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200269
Mice
Strain Name:C57BL/6Smoc-Httem1(hHTTQ145)Smoc
Strain State:Developing | Cat. NO.:NM-KI-234514
Mice
Strain Name:C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225087
Mice
Strain Name:C57BL/6Smoc-Ttrtm(hTTR-V50M)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220587
Mice
Strain Name:C57BL/6Smoc-Ugt1a1tm1(hUGT1A1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232902
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