SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220041
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Strain Name：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000083
Research Application：Alzheimer's disease research;drug screening
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Strain Name：C57BL/6Smoc-Vsirem1(hVSIR)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00118
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Vsig4em1(hVSIG4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210004
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State：Developing | Cat. NO.：NM-HU-2000112
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000019
Research Application：Immunotherapy,drug screening
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