hCD3EDG
Nomenclature
C57BL/6-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)/CbSmoc
Cat. NO.
NM-HU-220120
Strain State
Repository Live
Gene Summary
Gene Symbol
CD3E
Gene Symbol
CD3D
Gene Symbol
CD3G
Model Description
Validation Data
Fig 1. Expression detection of human CD3E/CD3D/CD3G by FACS in homozygous hCD3EDG mice.
Fig 2. Homozygous hCD3EDG mice were engrafted with MC38-hCLDN18.2 to eveluate the in vivo efficacy of anti-CD3×Claudin18.2 bispecific antibody in parallel with homozygous hCD3EDG mice.
Fig 3. Homozygous hCD3EDG mice were engrafted with MC38-hEpCAM to eveluate the AICD and irAE of OKT3 and anti-CD3×EpCAM bispecific antibody in vivo.
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