Cdkl5-KO

Nomenclature

C57BL/6Smoc-Cdkl5em1Smoc

Cat. NO.

NM-KO-2105744

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Cdkl5

Synonyms

Stk9; BC038161

NCBI ID

382253

MGI ID

1278336

Ensembl ID

ENSMUSG00000031292

Pubmed

Cdkl5

Human Ortholog

CDKL5

Model Description

Exon 6 of Cdkl5 gene was deleted to generate Cdkl5 knockout mice.

Disease Connection

Developmental And Epileptic Encephalopathy 2

Phenotype(s)

MGI:5574073

Reference(s)

Amendola E, Zhan Y, Mattucci C, Castroflorio E, Calcagno E, Fuchs C, Lonetti G, Silingardi D, Vyssotski AL, Farley D, Ciani E, Pizzorusso T, Giustetto M, Gross CT, Mapping Pathological Phenotypes in a Mouse Model of CDKL5 Disorder. PLoS One. 2014;9(5):e91613

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