Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Strain Name：C57BL/6Smoc-Axltm1(hAXL)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215067
The endogenous mouse Axl gene was replaced by human AXL gene.
Strain Name：C57BL/6Smoc-Igs2 em1(CAG-EGFP-pA)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00066
These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.
Strain Name：C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc Strain State：Repository Live | Cat. NO.：NM-HU-200220
The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.
Strain Name：BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200213
A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.
Strain Name：C57BL/6Smoc-Ahrem1(hAHR)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200252
The endogenous mice Ahr gene was replaced by human AHR gene.
Strain Name：C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc Strain State：Developing | Cat. NO.：NM-HU-200247
The endogenous mice Angpt2 gene was replaced by human ANGPT2 gene.
Strain Name：C57BL/6Smoc-C1s1em1(hC1S)/Smoc Strain State：Repository Live | Cat. NO.：NM-HU-2000077
The endogenous mouse C1s1 gene was replaced by human C1S gene.
Strain Name：NOD-PrkdcscidHgfem1(hHGF)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190062
The endogenous mouse Hgf gene was replaced by human HGF gene.
Strain Name：C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00084
An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .
Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18013
hPD-L1(NM-HU-00062) was crossed with hTIGIT(NM-HU-00053) to generate hPD-L1/hTIGIT.
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