U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000091
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210371
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Havcr2em1(hHAVCR2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00054
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Havcr2em3(hHAVCR2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234272
Mice
Strain Name:BALB/cAnSmoc-Havcr2tm1(hHAVCR2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234273
Mice
Strain Name:C57BL/6Smoc-Timd4tm1(hTIM4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225042
Mice
Strain Name:C57BL/6Smoc-Tim4tm1(hTIM4)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234276
Mice
Strain Name:C57BL/6Smoc-Timd4em1(hTIMD4)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215055
Mice
Strain Name:C57BL/6Smoc-Tgtn(hTIPE2)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225017
Mice
Strain Name:C57BL/6Smoc-Tnfsf15tm1(hTNFSF15)Smoc
Strain State:Developing | Cat. NO.:NM-HU-233157
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