U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:DBA-Tg(hTNFa)1Smoc
Strain State:Developing | Cat. NO.:NM-TG-225007
Research Application:Arthritis mouse model
Mice
Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190010
Research Application:Immune-related
Mice
Strain Name:BALB/cAnSmoc-Tnfrsf1bem(hTNFRSF1B)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220499
Mice
Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Fcgr2bem3(FCGR2B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210404
Research Application:inmmue therapy; drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210408
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210407
Research Application:inmmue therapy; drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220041
Mice
Strain Name:C57BL/6Smoc-Tnfrsf10bem1(hTNFRSF10B)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210005
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf23em(hTNFRSF10C)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230344
Mice
Strain Name:C57BL/6Smoc-Tnfrsf12aem(hTNFRSF12A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230046
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