SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Cd3etm(hCD3E)Cd3dtm(hCD3D)Cd3gtm(hCD3G)Folh1tm(hFOLH1B) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220251
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Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgem1(hTPBG) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220111
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Strain Name：C57BL/6Smoc-Cd4em1(hCD4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00115
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Cd4em3(hCD4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000053
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00076
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：BALB/cAnSmoc-Cd40em1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000047
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200256
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-CD40em2(hCD40)Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200268
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Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406
Research Application：inmmue therapy; drug screening
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Strain Name：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Research Application：Immunotherapy,drug screening
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