Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-LSL-RHOA(Y42C)-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200048
Research Application：Cancer research
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-loxp-Stop-loxp-SOS-F-IRES-tdTomato-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200020
Research Application：Spontaneous skin cancer model
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-hSOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210138
Research Application：Fluorescent reporter Mice
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-SOX2-IRES-Luciferase-2a-EGFP-WPRE-polyA)Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-234153
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(SA-polyA-CAG-LSL-TPM3-NTRK1-IRES-luc-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190098
Research Application：Colorectal carcinoma related.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190128
Research Application：Wnt1 signaling pathway, cancer research, etc
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190087
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18053
Research Application：Tumor research; drug screening
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-LSL-Kozak-hNTN1-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-233967
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-loxp-stop-loxp-hMycRTG3-ERT2-IRES-EGFP-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225096
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