Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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Strain Name：C57BL/6Smoc-Igs2em1(CAG-loxp-Neo-Stop-loxp-lox2272-Neo-Stop-lox2272-HA tag-NMYC-IRES-EFGP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210145
Research Application：Cancer research
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Strain Name：C57BL/6Smoc-Abcc2tm1(hABCC2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200254
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Strain Name：C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200247
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Strain Name：C57BL/6Smoc-Tnfsf13em(hTNFSF13)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220521
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Strain Name：C57BL/6Smoc-Axltm1(hAXL)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215067
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Strain Name：C57BL/6Smoc-Ccn1em(hCCN1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220518
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Strain Name：C57BL/6Smoc-Ccn2em(hCCN2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220517
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Strain Name：C57BL/6Smoc-Ccn4tm(hCCN4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220519
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Strain Name：BALB/cAnSmoc-Ccr8em(hCCR8)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220501
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