U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Cldn6em1(hCLDN6)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225034
Mice
Strain Name:C57BL/6Smoc-Clec5atm(hCLEC5A)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220503
Mice
Strain Name:C57BL/6Smoc-Clec4ntm(hCLEC6A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220516
Mice
Strain Name:NOD.Cg-PrkdcscidIl2rgem1Csf1tm2(hCSF1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220311
Mice
Strain Name:C57BL/6Smoc-Ddr1tm1(hDDR1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-225086
Mice
Strain Name:C57BL/6Smoc-Dll3em1(hDLL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200231
Mice
Strain Name:C57BL/6Smoc-Dll4tm1(hDLL4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000020
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Egfrtm1(hEGFR)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200227
Mice
Strain Name:C57BL/6Smoc-Engtm(hENG)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220283
Mice
Strain Name:C57BL/6JSmoc-Entpd1em(hENTPD1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220500
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