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Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases

Model Organisms：Mice Product & Service：Tlr2-KO;Cd45.1;Rag2-KO Research field：autoimmune diseases

Published date：2021-11-17 | References：iScience

The oncolytic virus VT09X optimizes immune checkpoint therapy in low immunogenic melanoma

Model Organisms：Mice Product & Service：hPD-1 Research field：Immune checkpoint therapy

Published date：2021-11-12 | References：IMMUNOL LETT

Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle

Model Organisms：Mice Product & Service：Rosa26-DreER ，Ki67-CrexER Research field：Cardiovascular Research

Published date：2021-10-01 | References：Nature Communications

ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells

Model Organisms：Mice Product & Service：Zfp91-floxed Research field：T cell

Published date：2021-10-01 | References：J Clin Invest

SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade

Model Organisms：Mice Product & Service：Snx10-floxed Research field：IBD

Published date：2021-09-30 | References：EMBO J

Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling

Model Organisms：Mice Product & Service：Rag1-KO;Il33-KO(2) Research field：Gut Microbial Metabolite Pravastatin

Published date：2021-09-28 | References：Frontiers in Immunology

METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1

Model Organisms：Mice Product & Service：Mettl14-Flox Research field：podocyte injury and glomerulopathy

Published date：2021-09-27 | References：Cell Death and Disease

https://www.thno.org/v11p9623.htm

Model Organisms：Mice Product & Service：Rosa26-LSL-linc-AhRA Research field：autoimmune

Published date：2021-09-21 | References：THERANOSTICS

RACK1 T50 Phosphorylation by AMPK Potentiates Its Binding with IRF3/7 and Inhibition of Type 1 IFN Production

Model Organisms：Mice Product & Service：Rack1-Flox Research field：Inflammation

Published date：2021-09-01 | References：Journal of Immunology

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer

Model Organisms：Mice Product & Service：Mkrn3-Flox Research field：Cancer Research

Published date：2021-08-02 | References：J Exp Med

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