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RACK1 T50 Phosphorylation by AMPK Potentiates Its Binding with IRF3/7 and Inhibition of Type 1 IFN Production

Model Organisms：Mice Product & Service：Rack1-Flox Research field：Inflammation

Published date：2021-09-01 | References：Journal of Immunology

E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer

Model Organisms：Mice Product & Service：Mkrn3-Flox Research field：Cancer Research

Published date：2021-08-02 | References：J Exp Med

MicroRNA-96 is required to prevent allodynia by repressing voltage-gated sodium channels in spinal cord

Model Organisms：Mice Product & Service：mir 96 cko;gad2-creERT2 Research field： research of pain relief ; central nervous system disorders

Published date：2021-07-23 | References：ELSEVIER

hACE2 Fc-neutralization antibody cocktail provides synergistic protection against SARS-CoV-2 and its spike RBD variants

Model Organisms：Mice Product & Service：hACE2 Research field：COVID-19

Published date：2021-07-20 | References：cell discovery

Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation

Model Organisms：Mice Product & Service：Snx10-flox Research field：Inflammation

Published date：2021-07-15 | References：Pharmacological Research

Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension

Model Organisms：Mice Product & Service：Fcgr2b-Flox Research field：Cardiovascular Research

Published date：2021-07-09 | References：Circulation Research

LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis

Model Organisms：Mice Product & Service： Larp7-KO Research field：heart failure

Published date：2021-05-18 | References：Circulation

Programmed death protein 1 is essential for maintaining the anti-inflammatory function of infiltrating regulatory T cells in a murine spinal cord injury model

Model Organisms：Mice Product & Service：Rag1-KO(Rag1-EGFP) Research field：Spinal cord injury

Published date：2021-05-15 | References：Journal of Neuroimmunology

The endoribonuclease N4BP1 prevents psoriasis by controlling both keratinocytes proliferation and neutrophil infiltration

Model Organisms：Mice Product & Service：N4BP1-KO Research field：keratinocytes proliferation and neutrophil infiltration

Published date：2021-05-14 | References：Cell Death & Disease

Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3

Model Organisms：Mice Product & Service：Snx3-floxed Research field：Cardiovascular

Published date：2021-05-04 | References：CELL DEATH DIFFER

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