Analysis of Antibody Specificity
For monoclonal antibody drugs, the multi-specificity of antibody target also brings great risks to the safety of usage, which is a big challenge for their development. Therefore, we launch the service for non-specific binding assessment.
Our specific detection library has included over 2000 target antigen proteins, over 1600 overexpression cell lines, and over 1000 target reference antibodies, which can be used for the rapid evaluation of binding specificity. In the future, the library will also contain over 4500 membrane protein overexpression cell lines to achieve full-target evaluation and facilitate the selection of optimal antibody molecules. In addition, we also provide TCR tests on humans, rhesus monkeys, and rats to assist clients in clinical application.
1. Over 6500 target recombinant proteins
Extensive target protein library and 7-day protein preparation process enable rapid and comprehensive completion of antibody non-specific evaluation.
2. Over 4500 Membrane protein overexpression cell lines
Multiple target cell libraries and non-specific antibody evaluation based on flow analysis enables accurate determination of non-specific targets.
3. TCR tests on humans, Rhesus monkeys, and rats
33 human tissues, 30 Rhesus monkey tissues, and 30 rat tissues.
4. Rich project testing experience
Accumulated detection experience of dozens of projects, covering proteins, cells, and tissues.
SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.Learn more
After the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.Learn more