U-GEMMs

Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190077
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3eem2(hCD3E)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210409
Research Application:Drug Screening; Immunotherapy Evaluation
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200272
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200279
Mice
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210357
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00048
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Adora2atm1(hADORA2A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215061
Mice
Strain Name:C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200278
Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00107
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd276tm2(hCD276)Cd28em2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210353
Research Application:inmmue therapy;drug screening
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