Who We are


Founded in 2000, we are committed to providing cutting-edge animal model services with more than 20 years of experience in genetics and genomics research.

Clinging to the mission, Editing Genes and Decoding Life, we focus on life science research and pharmacy discovery. Innovation of CRISPR/Cas9-based gene editing and embryonic stem (ES) cell-based gene targeting technologies serving as driving force, we have established versatile platforms applied to genetic edition of mice and rats, phenotype analysis, drug screening and drug evaluation, and gene bank intended for designing humanized animal models.

Since 2000, we have developed more than 18,000 custom genetically engineered animal models for genetic research and drug development, involving therapeutics of cancer, neuroregeneration diseases, metabolic disorder, inflammation and rare diseases. Besides, we originally developed more than 8,000 models, including those applied to the frontier of drug research intended for the inhibition of immune checkpoints (e.g. PD-1, PD-L1, CTLA-4, CD47 and TIGIT), and treatment of rare diseases, such as A/B type hemophilia.

We have established partnership with laboratories of universities, institutes, hospitals and some renowned pharmacy companies and CRO companies, which specialize in biotech-based drug research.

Our Mission

Editing genes, decoding the mysteries of life.

Our Vision

To be the leading provider of genetically engineered animal modeling services, and bring human healthier life.

Popular articles

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

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Shanghai Model Organisms Jinshan R&D Base officially put into operation

After the base is put into operation, SMOC’s capability to provide genetically modified rat/mouse models and technical services including gene function research and drug development will be greatly enhanced.

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