U-GEMMs

Immune Checkpoints

SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice. 

Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00111
Research Application:cancer research,Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000103
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000099
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tmem173tm1(hTMem173)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000105
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18013
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190056
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Visrem1(hVSIR)Cd274em1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000094
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00046
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Selplgem2(hSELPLG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210026
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210008
Research Application:drug screening
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