U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Rab31em1(hRAB31*Y76F/Y86F/Y137F)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-210419
Mice
Strain Name:C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200280
Mice
Strain Name:C57BL/6Smoc-Il2rgem1Kdrtm2(hKDR)Rag2em1Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220087
Mice
Strain Name:C57BL/6Smoc-Igs7em1(tetO-EGFR-del19-IRES-GFP-2A-Cre)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200258
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