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SEC16A Variants Predispose to Chronic Pancreatitis by Impairing ER-to-Golgi Transport and Inducing ER Stress

Model Organisms：Mice Product & Service：Sec16a-KO Research field：

Published date：2024-08-09 | References：WILEY

Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice

Model Organisms：Mice Product & Service：hDPP4 Research field：coronavirus infection

Published date：2024-02-05 | References：Nature Communications

The Abundant Distribution and Duplication of SARS-CoV-2 in the Cerebrum and Lungs Promote a High Mortality Rate in Transgenic hACE2-C57 Mice

Model Organisms：Mice Product & Service：hACE2 Research field：SARS-CoV-2

Published date：2024-01-13 | References：International Journal of Molecular Sciences

TMEM135 maintains the equilibrium of osteogenesis and adipogenesis by regulating mitochondrial dynamics

Model Organisms：Mice Product & Service：Tmem135-KO Research field：Osteoporosis

Published date：2023-12-26 | References：Metabolism: Clinical and Experimental

Choroid plexus mast cells drive tumor-associated hydrocephalus

Model Organisms：Mice Product & Service：Tpsb2-KO;Cpa3-2A-CreERT2 ;Tpsb2-Flox Research field：

Published date：2023-12-21 | References：Cell Reports

The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation

Model Organisms：Mice Product & Service：huHSC-(M-NSG) Research field：The therapeutic mechanism of immunotherapy for non-small cell lung cancer

Published date：2023-12-07 | References：Cellular & Molecular Immunology

RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3- dependent macrophage homeostasis

Model Organisms：Mice Product & Service：Mettl3-Flox Research field：allergic asthma

Published date：2023-11-13 | References：nature communications

Slowed Intestinal Transit Induced by Less Mucus in Intestinal Goblet Cell Piezo1-Deficient Mice through Impaired Epithelial Homeostasis

Model Organisms：Mice Product & Service：Muc2-2A-CreERT2-IRES-tdTomato ;Piezo1-Flox Research field：

Published date：2023-09-21 | References：MDPI

CCL2-mediated inflammatory pathogenesis underlies high myopia-related anxiety

Model Organisms：Mice Product & Service：R26-CAG-EGFP Research field：high myopia and anxiety

Published date：2023-09-12 | References：Cell Discovery

Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain

Model Organisms：Mice Product & Service：R26-CAG-LSL-RSR-tdTomato-2A-DTR Research field：Obesity

Published date：2023-09-12 | References：Cell Metabolism

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