Alb-CreERT2

Nomenclature

B6.129S-Albtm1.1(CreERT2)Smoc

Cat. NO.

NM-KI-00002

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
ALB

Synonyms

Alb1; Alb-1; BCL002

NCBI ID

11657

MGI ID

87991

Ensembl ID

ENSMUSG00000029368

Pubmed

ALB

Human Ortholog

ALB

Model Description

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.
Research Application：cre-mediated recombination system

Validation Data

alb-creERT2-1.png

Fig1 X-gal staining of liver slides of Alb-CreERT2 and LacZ positive mouse before and after tamoxifen injection. 

alb-creERT2-2.png

Fig2  Immunofluorescence analysis of liver using anti-Alb(Green) and anti-LacZ(Red) antibodies showed that Cre is expressed in most hepatocytes.

alb-creERT2-3.png

Fig3  Blood biochemical assay of Alb-CreERT2 male and female mice. Alb-CreERT2 mice do not display any liver functional abnormalities.

Publications

Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress
References：Cell Reports

Reference(s)

Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress
References：Cell Reports

Fate tracing of hepatocytes in mouse liver
References：SCIENTIFIC REPORTS

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more