Myf6-CreERT2

Nomenclature

C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc

Cat. NO.

NM-KI-200125

Strain State

Repository Live

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Gene Summary

Gene Symbol
Myf6

Model Description

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.
Research Application:Cre recombinase tool

Validation Data

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Fig. 1 CreERT2-mediated recombination in the muscle of Myf6CreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the muscle of Myf6CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment.

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Fig. 2 Detection of tdTomato(red) in various tissues of Myf6CreERT2/+; Rosa26tdTomato/+ mice. Tdtomato is expressed in the muscle and thymus after tamoxifen treatment. Tdtomato expression can not be observed in the brain, colon, epididymis, kidney, spleen, stomach, brown fat, intestine, heart, retina, liver, lung, pancreas, testis and salivary gland. (For more detailed information please contact our technical advisor.)

 




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