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Models

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Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225050

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

hB7H3

Strain Name：C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00107

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

hOX40/Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Tnfrsf4em1(hTNFRSF4)Cd8aem1(V5-IRES-luc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210375

hOX40(NM-HU-00041) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hOX40/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

Rag2-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Kdrtm2(hKDR)Rag2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200280

The Rag2 gene of NM-HU-00098 was knock out.

Mice

B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

h4-1BB(2)/hOX40

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200272

hTNFRSF9(NM-HU-190077) was crossed with hOX40(NM-HU-00041)to generate h4-1BB(2)/hOX40 mice

Mice

Alb-2A-DTRGFP(NMG)

Strain Name：NOD-Prkdcscid Il2rgem1Albem1(2A-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

R26-CAG-LSL-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-LSL-R-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210094

These mice harbor a CAG-LSL-R-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

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