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U-GEMMs

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Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000088

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hB7H3

Strain Name：C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00107

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

Cd8a-IRES-DTRGFP/Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Cd8aem2(IRES-DTREGFP)Cd8aem1(V5-IRES-luci-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210399

Cd8a-IRES-DTRGFP(NM-KI-190045) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate Cd8a-IRES-DTRGFP/Cd8a-IRES-luc-2A-EGFP mice.

Mice

hPD-L1/hCD28

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Cd28em2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hADORA2A

Strain Name：C57BL/6Smoc-Adora2atm1(hADORA2A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215061

The endogenous mouse Adora2a gene was replaced by human ADORA2A gene.

Mice

Trp53-Flox

Strain Name：C57BL/6Smoc-Trp53tm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18005

These Trp53 flox mice possess loxP sites flanking exons 5-7  via ESC targeting. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

hCD81/hOCLN

Strain Name：C57BL/6Smoc-Cd81em1(hCD81)Oclnem1(hOCLN)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000107

These mice are obtained through breeding of two single gene humanized mice.

Mice

B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

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