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Models

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Mice

hAppNL-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000087

The endogenous mouse App gene was replaced by human AppNL-F.

Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd8aem1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190011

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

H11-pT3(b)-hIL15-Flag

Strain Name：C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220128

pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA expression cassette was knocked into the the lgs2 (H11) locus.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name：C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

hCD38(2)

Strain Name：C57BL/6Smoc-Cd38em2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190059

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

Mice

h4-1BB(2)/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210357

h4-1BB(2)(NM-HU-190077), hPD-L1(NM-HU-00062) and hPD-1(NM-HU-00015) was crossed together to generate h4-1BB(2)/hPD-1/hPD-L1 mice.

Mice

Aicda-Cre

Strain Name：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200160

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

Mice

Rag2/IL2rg-KO/hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpaem1(hSIRPA)Cd47em1(hCD47)Rag2em1Il2rgem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000019

The Rag2 and Il2rg genes of the hSIRPA(2)/hCD47 mouse were deleted.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

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