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U-GEMMs

About 42,431 results
Mice

hCTLA-4/Cd8a-IRES-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Cd8aem1(V5-IRES-luc-2A-EGFP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210374

hCTLA4(NM-HU-00014) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hCTLA4/Cd8a-IRES-Akaluc-2A-EGFP mice.

Mice

hCD24/hSIGLEC10

Strain Name：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210367

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061）to generate hCD24/hSIGLEC10 mice.

Mice

hSTING

Strain Name：C57BL/6Smoc-Tmem173tm2(hTMEM173)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190036

The endogenous mouse Tmem173 gene was replaced by human TMEM173 gene.

Mice

hCD47

Strain Name：C57BL/6Smoc-Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00050

The endogenous mouse Cd47 gene was replaced by human CD47 gene.

Mice

hTIGIT

Strain Name：C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

hCCR2

Strain Name：C57BL/6Smoc-Ccr2em2(hCCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18026

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvem1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlaem2(hBTLA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190040

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225050

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

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