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Models

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Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name：BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200213

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

hCD40

Strain Name：C57BL/6Smoc-Cd40em1(hCD40) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00076

The endogenous extracellular mouse Cd40 gene was replaced by the  extracellular region of human CD40 gene.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rem2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

hAHR

Strain Name：C57BL/6Smoc-Ahrem1(hAHR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200252

The endogenous mice Ahr gene was replaced by human AHR gene.

Mice

hALB

Strain Name：C57BL/6Smoc-Albem3(ALB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200003

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

Pten-Flox

Strain Name：C57BL/6Smoc-Ptenem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18004

These Pten flox mice possess loxP sites flanking exons 5 via CRISPR/Cas mediated recombination. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Aplnr-2A-DreERT2

Strain Name：C57BL/6Smoc-Aplnrem1(2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00132

A 2A-DreERT2-SV40polyA coexpression cassette is inserted befor the stop codon of mouse Aplnr gene via homologous recombination to establish a tamoxifen inducible Aplnr-DreERT2 tool stain. This strain can be used to knockout target gene in Aplnr+ cells after tamoxifen treatment when crossed with mice which carry rox sites flanking target gene.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

hC5AR1

Strain Name：C57BL/6Smoc-C5ar1em1(hC5AR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204989

The endogenous mice C5ar1 gene was replaced by human C5AR1 gene.

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