U-GEMMs

Tumor Targets

Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.

Mice
Strain Name:C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225068
Mice
Strain Name:C57BL/6Smoc-Igf2em(hIGF2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230030
Mice
Strain Name:C57BL/6Smoc-Igheem(hIGHE)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220512
Mice
Strain Name:C57BL/6Smoc-Itgavem1(hITGAV)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225043
Mice
Strain Name:C57BL/6Smoc-Itgb1em1(hITGB1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225040
Mice
Strain Name:C57BL/6Smoc-Itgb8em1(hITGB8)Smoc
Strain State:Developing | Cat. NO.:NM-HU-225025
Mice
Strain Name:C57BL/6Smoc-Liftm(hLIF)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220506
Mice
Strain Name:C57BL/6Smoc-Tg(hLILRB1-hLILRB2)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-220204
Mice
Strain Name:C57BL/6Smoc-Tgtn(hLILRB1)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-232398
Mice
Strain Name:C57BL/6Smoc-Tg(loxp-LILRB2-LILRB3-FRT-PGK-PuropolyA-FRT-lox2272)
Strain State:Repository Live | Cat. NO.:NM-TG-220136
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