Humanized tumor target mice are immunocompetent chimeric mouse models, engineered to express humanized tumor targets such as genes encoding for oncogene proteins, tumor suppressor proteins, tumor specific antigen, etc. These models can can be used to evaluate the risk of on-target, off-tumor toxicities for targeted cancer drug.
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Strain Name：C57BL/6Smoc-Muc1tm(hMUC1-c.462insC)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220410
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Strain Name：C57BL/6Smoc-Tgtn(hNCR2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-225019
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Strain Name：C57BL/6Smoc-Tgtn(hNCR3)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-225018
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Strain Name：C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210016
Research Application：drug screening
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Strain Name：C57BL/6Smoc-Nr3c1tm1(hNR3C1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225058
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Strain Name：C57BL/6Smoc-Ntrk1em(hNTRK1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-230058
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Strain Name：C57BL/6Smoc-Olr1tm(hOLR1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-230107
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Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210370
Research Application：inmmue therapy;drug screening
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